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Study Finds COVID-19 Vaccine Does Not Increase Risk of Miscarriage

New Delhi, Oct 31. A recent study published in the journal Human Reproduction has revealed that receiving a COVID-19 vaccine before conceiving does not raise the risk of early or late miscarriage.

This research provides valuable insights into the safety of COVID-19 vaccines for individuals planning to become pregnant.

It is the first study to examine the risk of early miscarriage (less than eight weeks gestation) following COVID-19 vaccination.

The study was conducted by a team of researchers from Boston University School of Public Health (BUSPH) in the United States.

The researchers hope that these findings will offer useful information for individuals planning to conceive, as well as their healthcare providers. While it is important to replicate these results in other populations, the study provides reassurance for couples who are planning to have a baby, according to lead author Jennifer Yland, who was a PhD student at BUSPH during the study.

Yland and her colleagues analyzed data from the BUSPH-based Pregnancy Study Online (PRESTO), an ongoing study that enrolls women trying to conceive and follows them from preconception through six months after delivery.

The study included 1,815 female participants from the United States and Canada who were followed from December 2020 to November 2022.

The participants were observed from their first positive pregnancy test until a miscarriage or other event, such as induced labor, occurred.

Among the female participants, 75 percent had received at least one dose of a COVID-19 vaccine before becoming pregnant.

Nearly a quarter of the pregnancies resulted in miscarriage, with 75 percent of these miscarriages occurring before eight weeks gestation. However, the researchers found no increased risk of miscarriage associated with COVID-19 vaccination.

The risk of miscarriage was 26.6 percent among unvaccinated female participants, 23.9 percent among those who had received one dose of the vaccine before conception, and 24.5 percent among those who completed a full primary series before conception.

Among those who completed the vaccine series three months before conception, the risk was 22.1 percent, and it was 20.1 percent among those who received only one dose of a two-dose vaccine before conception. PTI

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